Author

J. sa-Pessoa Graca Santos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Assay:proteomics· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

J. A. Bengoechea· 3 shared A. Dumigan· 2 shared B. Morris· 2 shared R. Calderon-Gonzalez· 2 shared A. G. Bowie· 1 shared A. Kissenpfening· 1 shared A. Kissenpfennig· 1 shared A. Mcnally· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersMicrobiology

J. A. Bengoechea

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintOct 18, 2021

In vivo single cell transcriptomics reveals Klebsiella pneumoniae rewiring of lung macrophages to promote infection

A. Dumigan, O. Cappa, B. Morris…·J. A. Bengoechea

This study identifies a novel host-pathogen interaction where Klebsiella pneumoniae rewires lung macrophages to promote infection by inducing an M(Kp) polarization state.

DOI 10.1101/2021.10.18.464784

humanscRNA-seq

𝕏 PostBluesky

MicrobiologybioRxivSep 29, 2021

Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity.

C. Feriotti, J. sa-Pessoa Graca Santos, R. Calderon-Gonzalez…·J. A. Bengoechea

This study shows Klebsiella pneumoniae uses SARM1, a host protein, to suppress immune responses via type I IFN signaling, enhancing its survival in macrophages.

DOI 10.1016/j.celrep.2022.111167

mouseproteomics

𝕏 PostBluesky

MicrobiologybioRxivJul 10, 2019

Klebsiella pneumoniae type VI secretion system-mediated microbial competition is PhoPQ controlled and reactive oxygen species dependent

J. A. Bengoechea, D. Storey, A. Mcnally…·T. A. Salminen

This study identifies PhoPQ as a regulator of Klebsiella pneumoniae T6SS activity, which mediates microbial competition and is dependent on reactive oxygen species.

DOI 10.1371/journal.ppat.1007969

bacteria (other)proteomics

𝕏 PostBluesky