J. Shoots

Interactions between the N- and C- termini of mechanosensitive ion channel AtMSL10 are consistent with a three-step mechanism for activation

The paper investigates how mutations in the N- and C-termini of the plant mechanosensitive ion channel AtMSL10 trigger cell death and proposes a three-step activation mechanism involving conformational changes and dephosphorylation.

Nonpolar Residues in the Presumptive Pore-Lining Helix of Mechanosensitive Channel MSL10 Influence Channel Behavior and Confirm a Non-Conducting Function

This study identifies nonpolar residues in MSL10's pore-lining helix that influence conductance, gating tension, and cell death signaling, showing ion channel function is independent of cell death.