Author

J. Spagnuolo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Approach:biophysical modeling· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. Beshirova· 1 shared A. Chancellor· 1 shared A. Vacchini· 1 shared C. De Gregorio· 1 shared C. Olivera· 1 shared D. Häussinger· 1 shared D. Joss· 1 shared G. De Libero· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

A. Beshirova

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2 papers

Recent·Most cited

Nucleobase adduct-containing metabolites are MR1 ligands that stimulate self-reactive MR1T cells

A. Vacchini, A. Chancellor, Q. Yang, J. Spagnuolo, D. Joss, O. Oyas, A. Beshirova, C. De Gregorio, M. Pfeffer, J. Stelling, D. Häussinger, M. Lepore, L. Mori, G. De Libero

The paper identifies nucleobase adduct-containing metabolites as MR1 ligands that activate self-reactive MR1T cells, highlighting their role in detecting metabolic stress in cancer.

bioRxiv · Aug 26, 2022 · PreprintImmunology

In vitro synergy between Sodium Deoxycholate and Furazolidone against Enterobacteria via Inhibition of Multidrug Efflux Pumps

V. V. H. Le, C. Olivera, J. Spagnuolo, I. Davies, J. Rakonjac

This study shows that combining furazolidone and sodium deoxycholate synergistically inhibits enterobacterial growth by enhancing efflux pump inhibition and nitric oxide production.

bioRxiv · Jan 11, 2019 · PreprintMicrobiology