An ancestral role of pericentrin in centriole formation through SAS-6 recruitment
D. Ito, S. Zitouni, S. C. Jana, P. Duarte, J. Surkont, Z. Carvalho-Santos, J. B. Pereira-Leal, M. Godinho Ferreira, M. Bettencourt-Dias
The study identifies an ancestral interaction between pericentrin and SAS-6 that regulates centriole biogenesis and elongation, conserved across species despite centriole loss in yeasts.
bioRxiv · May 3, 2018Cell Biology