Author

J. T. Fourkas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 5 Approach:experimental assay· 5 Assay:imaging· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Organism:human· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

W. Losert· 5 shared M. J. Hourwitz· 3 shared Q. Yang· 3 shared A. L. Bull· 2 shared L. Campanello· 2 shared P. N. Devreotes· 2 shared Y. Miao· 2 shared A. Omidvar· 1 shared

Activity by Year

2019-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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5 shared papersBiophysics

W. Losert

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Author profile →

5 papers

Recent·Most cited

Nanotopography modulates intracellular excitable systems through cytoskeleton actuation

Q. Yang, Y. Miao, P. Banerjee, M. J. Hourwitz, M. Hu, Q. Qing, P. A. Iglesias, P. N. Devreotes, J. T. Fourkas, W. Losert

The paper shows nanotopography is sensed directly by cytoskeletal networks, with implications for texture sensing and guidance cues in microenvironments.

bioRxiv · Jun 9, 2022 · PreprintBiophysics

Cortical waves mediate the cellular response to electric fields

Q. Yang, Y. Miao, L. J. Campanello, M. J. Hourwitz, B. Abubaker-Sharif, A. L. Bull, P. N. Devreotes, J. T. Fourkas, W. Losert

The paper shows electric fields guide cell movement by controlling biochemical waves and cytoskeletal activity, with faster response on nanotopographic surfaces.

bioRxiv · Jun 8, 2021Cell Biology

Spontaneous polarization and cell guidance on asymmetric nanotopography

C. Herr, B. Winkler, F. Ziebert, I. S. Aranson, J. T. Fourkas, W. Losert

This study models cell migration on asymmetric nanosawteeth, showing that actin polymerization rate and sawtooth dimensions influence directional bias and motion phenotypes.

bioRxiv · May 27, 2021Biophysics

Actin dynamics as a multiscale integrator of cellular guidance cues

A. L. Bull, L. Campanello, M. J. Hourwitz, Q. Yang, M. Zhao, J. T. Fourkas, W. Losert

This paper shows how actin polymerization dynamics integrate subcellular and cellular-scale guidance cues to direct cell migration.

bioRxiv · May 26, 2021 · PreprintBiophysics

Quantifying topography-guided actin dynamics across scales using optical flow

R. M. Lee, L. Campanello, M. Hourwitz, P. Alvarez, A. Omidvar, J. T. Fourkas, W. Losert

The paper quantifies actin wave dynamics on periodic topographies using optical flow, finding similar nanotopography-guided actin behavior in two cell types despite differences in wave speed and morphology.

bioRxiv · Sep 3, 2019Biophysics