Author

J. T. Mitchell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 2 Approach:deep learning· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:experimental assay· 1 Assay:imaging· 1

Frequent Co-Authors

D. N. Sidiropoulos· 2 shared E. J. Fertig· 2 shared E. M. Jaffee· 2 shared J. W. Zimmerman· 2 shared L. D. Wood· 2 shared L. T. Kagohara· 2 shared A. B. Pucsek· 1 shared A. Deshpande· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCancer Biology

D. N. Sidiropoulos

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2 papers

Recent·Most cited

PanIN and CAF Transitions in Pancreatic Carcinogenesis Revealed with Spatial Data Integration

A. T. F. Bell, J. T. Mitchell, A. L. Kiemen, K. Fujikura, H. Fedor, B. Gambichler, A. Deshpande, P.-H. Wu, D. N. Sidiropoulos, R. Erbe, J. Stern, R. Chan, S. Williams, J. M. Chell, J. W. Zimmerman, , L. T. Kagohara

This paper develops a new protocol for spatial transcriptomics analysis of FFPE PanIN specimens and integrates it with imaging and scRNA-seq to study the progression from PanIN to PDAC.

bioRxiv · Jul 16, 2022Cancer Biology

Inflammatory Signaling in Pancreatic Cancer Transfers Between a Single-cell RNA Sequencing Atlas and Co-Culture

B. Kinny-Koster, S. Guinn, J. A. Tandurella, J. T. Mitchell, D. N. Sidiropoulos, M. Loth, M. R. Lyman, A. B. Pucsek, T. T. Seppala, C. Cherry, R. Suri, H. Zlomke, J. He, C. L. Wolfgang, J. Yu, , J. W. Zimmerman

This paper integrates single-cell RNA sequencing data with organoid co-cultures to study inflammatory signaling in pancreatic cancer and validates findings through transfer learning and mechanistic experiments.

bioRxiv · Jul 14, 2022 · PreprintCancer Biology