Author

S. Guinn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. B. Pucsek· 1 shared A. Gupta· 1 shared A. H. Sharpe· 1 shared A. I. Daud· 1 shared A. Kimmelman· 1 shared B. Kinny-Koster· 1 shared C. Cherry· 1 shared C. Delaney· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. B. Pucsek

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Author profile →

2 papers

Recent·Most cited

Inflammatory Signaling in Pancreatic Cancer Transfers Between a Single-cell RNA Sequencing Atlas and Co-Culture

B. Kinny-Koster, S. Guinn, J. A. Tandurella, J. T. Mitchell, D. N. Sidiropoulos, M. Loth, M. R. Lyman, A. B. Pucsek, T. T. Seppala, C. Cherry, R. Suri, H. Zlomke, J. He, C. L. Wolfgang, J. Yu, , J. W. Zimmerman

This paper integrates single-cell RNA sequencing data with organoid co-cultures to study inflammatory signaling in pancreatic cancer and validates findings through transfer learning and mechanistic experiments.

bioRxiv · Jul 14, 2022 · PreprintCancer Biology

Single-cell analyses identify circulating anti-tumor CD8 T cells and markers for their enrichment

K. E. Pauken, O. Shahid, K. A. Lagattuta, K. M. Mahuron, J. M. Luber, M. M. Lowe, L. Huang, C. Delaney, J. M. Long, M. E. Fung, K. Newcomer, K. K. Tsai, M. Chow, S. Guinn, J. R. Kuchroo, , M. Singer

The paper identifies circulating anti-tumor CD8 T cells using single-cell RNA sequencing and TCR sequencing, and develops marker panels for their detection in mice and melanoma patients.

bioRxiv · Sep 30, 2020Immunology