Modes of inhibition used by phage anti-CRISPRs to evade type I-C Cascade
R. E. O'Brien, J. P. Bravo, D. Ramos, G. N. Hibshman, J. T. Wright, D. W. Taylor
The paper presents a cryo-EM structure of the type I-C Cascade complex and describes how anti-CRISPR proteins inhibit it by blocking DNA binding.
bioRxiv · Jun 15, 2022 · PreprintBiochemistry