Binding and sequestration of poison frog alkaloids by a plasma globulin
A. Alvarez-Buylla, M. D. Moya Garzon, A. E. Rangel, E. E. Tapia, J. Tanzo, H. T. Soh, L. A. Coloma, J. Z. Long, L. A. O'Connell
The paper identifies a plasma globulin in poison frogs that binds and regulates alkaloid bioavailability, revealing a novel serpin-based mechanism for small molecule transport.
bioRxiv · Nov 22, 2022Physiology