Author

J. Tournois

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

C. Bruge· 2 shared E. PELLIER· 2 shared I. Richard· 2 shared M. BENABIDES· 2 shared N. Bourg· 2 shared X. Nissan· 2 shared A. Bigot· 1 shared A. Brureau· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersPharmacology & Toxicology

C. Bruge

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2 papers

Recent·Most cited

Identification of bazedoxifene for the treatment of LGMD R2 by high throughput screening.

C. Bruge, N. Bourg, E. PELLIER, J. Tournois, J. Polentes, M. BENABIDES, N. Grossi, A. Bigot, A. Brureau, I. Richard, X. Nissan

This study identifies bazedoxifene as a potential treatment for LGMD R2 through high-throughput screening of drugs targeting dysferlin aggregation.

bioRxiv · Feb 28, 2024 · PreprintPharmacology & Toxicology

Dual blockade of misfolded alpha-sarcoglycan degradation by bortezomib and givinostat combination

L. Hoch, N. Bourg, F. Degrugillier, C. Bruge, M. Benabides, E. Pellier, J. Tournois, G. Mahe, N. Maignan, J. Dawe, M. Georges, D. Papazian, N. Subramanian, S. Simon, P. Fanen, , X. Nissan

This study identifies givinostat as a potential therapeutic for LGMD R3 by inhibiting autophagy and enhancing bortezomib's effect on misfolded alpha-sarcoglycan degradation.

bioRxiv · Mar 16, 2022Pharmacology & Toxicology