Author

L. hoch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

c. Bruge· 2 shared e. Pellier· 2 shared I. Richard· 2 shared M. Benabides· 2 shared X. Nissan· 2 shared C. Delevoye· 1 shared D. Papazian· 1 shared F. Degrugillier· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

c. Bruge

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Author profile →

2 papers

Recent·Most cited

Skeletal muscle cells derived from induced pluripotent stem cells: a platform for limb girdle muscular dystrophies.

c. Bruge, M. GEOFFROY, M. Benabides, e. Pellier, L. hoch, I. Richard, X. Nissan

This paper describes a platform using human induced pluripotent stem cells to model limb girdle muscular dystrophies and demonstrates its utility in studying disease-specific phenotypes.

bioRxiv · May 8, 2022Cell Biology

Dual blockade of misfolded alpha-sarcoglycan degradation by bortezomib and givinostat combination

L. Hoch, N. Bourg, F. Degrugillier, C. Bruge, M. Benabides, E. Pellier, J. Tournois, G. Mahe, N. Maignan, J. Dawe, M. Georges, D. Papazian, N. Subramanian, S. Simon, P. Fanen, , X. Nissan

This study identifies givinostat as a potential therapeutic for LGMD R3 by inhibiting autophagy and enhancing bortezomib's effect on misfolded alpha-sarcoglycan degradation.

bioRxiv · Mar 16, 2022Pharmacology & Toxicology