Author

J. V. Sweedler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:rat· 2 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1 Assay:proteomics· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

B. P. Early· 1 shared D. C. Castro· 1 shared F. A. Butun· 1 shared F. A. Lewis· 1 shared F. Lam· 1 shared J. B. Greer· 1 shared J. Gao· 1 shared J. J. Collins· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperBiochemistry

B. P. Early

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Author profile →

3 papers

Recent·Most cited

Integrative Multiscale Biochemical Mapping of the Brain via Deep-Learning-Enhanced High-Throughput Mass Spectrometry

Y. R. Xie, D. C. Castro, S. S. Rubakhin, T. J. Trinklein, J. V. Sweedler, F. Lam

The paper introduces MEISTER, a framework for brain-wide and single-cell biochemical mapping using deep learning and mass spectrometry, identifying region-specific and cell-specific lipid profiles in rat brain tissue.

bioRxiv · May 31, 2023 · PreprintBiochemistry

Top-down Proteomics of 10,000 Single Brain Cells

P. Su, M. A. Hollas, S. Rubakhin, F. A. Butun, J. B. Greer, B. P. Early, R. T. Fellers, M. A. Caldwell, J. V. Sweedler, J. O. Kafader, N. L. Kelleher

The paper introduces scPiMS, a single-cell proteomics method, and identifies proteoforms from 10,836 rat hippocampal cells, classifying them into neuron, astrocyte, and microglia types.

bioRxiv · May 31, 2023 · PreprintBiochemistry

A rotifer-derived paralytic compound prevents transmission of schistosomiasis to a mammalian host

J. Gao, N. Yang, F. A. Lewis, P. Yau, J. J. Collins, J. V. Sweedler, P. A. Newmark

The paper identifies and characterizes a rotifer-derived compound that paralyzes schistosome cercariae and prevents infection more effectively than existing analogs.

bioRxiv · Jun 1, 2019Biochemistry