Author

J. O. Kafader

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:protein folding & dynamics· 1 Organism:rat· 1

Frequent Co-Authors

N. L. Kelleher· 4 shared B. P. Early· 3 shared R. T. Fellers· 3 shared F. A. Butun· 2 shared J. B. Greer· 2 shared K. R. Durbin· 2 shared P. Su· 2 shared A. A. Makarov· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersBiochemistry

N. L. Kelleher

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Top-down Proteomics of 10,000 Single Brain Cells

P. Su, M. A. Hollas, S. Rubakhin, F. A. Butun, J. B. Greer, B. P. Early, R. T. Fellers, M. A. Caldwell, J. V. Sweedler, J. O. Kafader, N. L. Kelleher

The paper introduces scPiMS, a single-cell proteomics method, and identifies proteoforms from 10,836 rat hippocampal cells, classifying them into neuron, astrocyte, and microglia types.

bioRxiv · May 31, 2023 · PreprintBiochemistry

Direct Imaging and Identification of Proteoforms up to 70 kDa from Human Tissue

P. Su, J. P. McGee, K. R. Durbin, M. A. R. Hollas, M. Yang, E. K. Neumann, J. L. Allen, B. S. Drown, F. A. Butun, J. B. Greer, B. P. Early, R. T. Fellers, J. M. Spraggins, J. Laskin, J. M. Camarillo, , N. L. Kelleher

This paper introduces PiMS, a method that detects proteoforms up to 70 kDa in human tissue with high spatial resolution, identifying key metabolic enzymes in kidney tissue.

bioRxiv · Dec 7, 2021 · PreprintBiochemistry

Decoding the Protein Composition of Whole Nucleosomes with Nuc-MS

L. F. Schachner, K. Jooss, M. A. Morgan, A. Piunti, M. J. Meiners, A. Lee, J. O. Kafader, M. Iwanaszko, M. A. Cheek, J. M. Burg, S. A. Howard, M.-C. Keogh, A. Shilatifard, N. L. Kelleher

The paper introduces Nuc-MS, a method to analyze protein composition of whole nucleosomes, revealing specific histone variants and modifications associated with oncogenic states.

bioRxiv · Sep 8, 2020Biochemistry

Multiplexed Single Ion Mass Spectrometry Improves Measurement of Proteoforms and Their Complexes

J. O. Kafader, R. D. Melani, K. R. Durbin, B. Ikwuagwu, B. P. Early, R. T. Fellers, S. C. Beu, V. Zabrouskov, A. A. Makarov, J. T. Maze, D. L. Shinholt, P. F. Yip, D. Tullman-Ereck, M. W. Senko, P. D. Compton, N. L. Kelleher

This paper introduces a new Orbitrap-based single ion analysis method that improves the measurement of proteoforms and their complexes by directly determining ion charge.

bioRxiv · Jul 26, 2019 · PreprintBiochemistry