Author

J. van Limbergen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1

Frequent Co-Authors

A. Coffin· 1 shared A. Patel· 1 shared A. Shillings· 1 shared A. Y. F. Li Yim· 1 shared C. E. Blunt· 1 shared D. A. Zwijnenburg· 1 shared D. F. Tough· 1 shared D. J. Mitchell· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

A. Coffin

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Author profile →

2 papers

Recent·Most cited

Assessing the variation within the oral microbiome of healthy adults

J. T. Nearing, V. DeClercq, J. Van Limbergen, M. G. I. Langille

This study examines the oral microbiome of 1049 healthy adults to identify factors shaping microbial composition, finding that anthropometric and demographic factors have small individual impacts.

mSphere · Oct 28, 2020Peer-reviewedMicrobiology

Modulation of macrophage inflammatory function through selective inhibition of the epigenetic reader protein SP140

M. Ghiboub, J. Koster, P. D. Craggs, A. Y. F. Li Yim, A. Shillings, S. Hutchinson, R. P. Bingham, K. Gatfield, I. L. Hageman, G. Yao, H. P. O'Keefe, A. Coffin, A. Patel, L. A. Sloan, D. J. Mitchell, , W. J. de Jonge

This study identifies SP140 as a druggable epigenetic reader and therapeutic target for Crohn's disease by showing that its inhibition reduces inflammatory macrophage activation and cytokine expression.

bioRxiv · Aug 10, 2020Immunology