Author

J. Vilar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

J.-S. SILVESTRE· 2 shared L. Saiz· 2 shared A. Eichmann· 1 shared A. Zernecke· 1 shared A.-E. Saliba· 1 shared C. Cochain· 1 shared D. HENRION· 1 shared D. J. Schulz· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersPhysiology

J.-S. SILVESTRE

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Author profile →

4 papers

Recent·Most cited

Chaperone-driven entropic separation of amyloid nanofilament bundles

J. Vilar, J. M. Rubi, L. Saiz

The paper develops a computational model to explain how chaperones drive the entropic separation of amyloid nanofilament bundles, showing that efficient chaperone systems are required to overcome lateral associations.

bioRxiv · May 24, 2023Biophysics

The unreasonable effectiveness of equilibrium gene regulation through the cell cycle

J. Vilar, L. Saiz

The paper develops a theory to analyze gene regulation during cell cycles and finds a scaling law connecting transcription to equilibrium values, showing how systems like the lac operon function beyond naive physical limits.

bioRxiv · Mar 31, 2023Biophysics

EphrinA4/EphA4 controls blood pressure via arterial sympathetic innervation

E. SIMONNET, S. MARTIN, J. VILAR, E. ROY-VESSIERES, S. TAIB, V. MONCEAU, L. Pardanaud, N. BOUBY, A. Eichmann, J.-S. SILVESTRE, D. HENRION, I. V. BRUNET

This study shows EphrinA4 in arterial SMCs repels sympathetic axons, and its loss increases sympathetic innervation, leading to elevated blood pressure and hypertension under stress.

bioRxiv · Feb 3, 2023 · PreprintPhysiology

Time-resolved single-cell transcriptomics uncovers dynamics of cardiac neutrophil diversity in murine myocardial infarction

E. Vafadarnejad, G. Rizzo, L. Krampert, P. Arampatzi, V. A. Nugroho, D. J. Schulz, M. Roesch, P. Alayrac, J. Vilar, J.-S. Silvestre, A. Zernecke, A.-E. Saliba, C. Cochain

This study uses time-resolved single-cell transcriptomics to analyze cardiac neutrophil diversity in murine myocardial infarction, identifying distinct subsets and their temporal dynamics.

bioRxiv · Aug 16, 2019Immunology