Author

P. Alayrac

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

J.-S. Silvestre· 2 shared A. Achab-Ali· 1 shared A. Zernecke· 1 shared A.-E. Saliba· 1 shared C. Cochain· 1 shared C. Delacroix· 1 shared D. A. Sassoon· 1 shared D. J. Schulz· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPharmacology & Toxicology

J.-S. Silvestre

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2 papers

Recent·Most cited

Inhibition of integrin alpha V (CD51) reduces inflammation and transition to heart failure following pressure overload

C. Delacroix, A. Achab-Ali, P. Alayrac, M. Gandon-Renard, F. Drame, D. A. Sassoon, J.-S. Silvestre, J.-S. Hulot

This study shows that inhibiting integrin alpha V reduces inflammation and prevents heart failure progression in pressure-overloaded mice by modulating pro-inflammatory macrophages.

bioRxiv · Oct 10, 2022 · PreprintPharmacology & Toxicology

Time-resolved single-cell transcriptomics uncovers dynamics of cardiac neutrophil diversity in murine myocardial infarction

E. Vafadarnejad, G. Rizzo, L. Krampert, P. Arampatzi, V. A. Nugroho, D. J. Schulz, M. Roesch, P. Alayrac, J. Vilar, J.-S. Silvestre, A. Zernecke, A.-E. Saliba, C. Cochain

This study uses time-resolved single-cell transcriptomics to analyze cardiac neutrophil diversity in murine myocardial infarction, identifying distinct subsets and their temporal dynamics.

Circulation Research · Oct 9, 2020Peer-reviewedImmunology