Author

J. W. Tan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Assay:multiome· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

C. L. Tham· 1 shared C. M. Rodriguez Lopez· 1 shared C. X. Yu· 1 shared D. Gutman· 1 shared E. Guimaraes· 1 shared E. J. Edwards· 1 shared F. Cai· 1 shared G. A. Splitter· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperBiochemistry

C. L. Tham

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Transcriptome Analysis Reveals Long-Term Somatic Memory of Stress in The Woody Perennial Crop, Grapevine Vitis Vinifera cv. Cabernet Sauvignon

J. W. Tan, k. Tesfamicael, Y. hu, H. Shinde, E. J. Edwards, P. Tricker, C. M. Rodriguez Lopez

This study investigates stress memory in grapevines using transcriptome and methylome sequencing, finding epigenetic changes and a classification model for stress memory genes.

bioRxiv · Apr 6, 2024 · PreprintPlant Biology

Insight parameter drug design for human beta-tryptase inhibition integrated molecular docking, QSAR, molecular dynamics simulation, and pharmacophore modelling studies of alpha-keto--oxadiazoles

C. X. Yu, J. W. Tan, S. Imran, K. Rullah, C. L. Tham

This study develops beta-tryptase inhibitors using 2D-QSAR, molecular docking, MD simulation, and pharmacophore modeling to improve DHF treatment.

bioRxiv · Jul 17, 2022 · PreprintBiochemistry

Brucella suppress innate immunity by down-regulating STING expression in macrophages

M. Khan, J. S. Harms, Y. Liu, J. Eickhoff, J. W. Tan, T. Hu, F. Cai, E. Guimaraes, S. C. Oliveira, R. Dahl, D. Gutman, G. N. Barber, G. A. Splitter, J. A. Smith

This study shows Brucella suppresses STING expression via miR-24 to evade innate immunity and establish chronic infection.

bioRxiv · Dec 31, 2019 · PreprintMicrobiology