Author

J. W. Young

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Assay:proteomics· 3 Organism:E. coli· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

F. Duong· 3 shared D. G. Rattray· 2 shared L. J. Foster· 2 shared M. Babu· 2 shared Z. Zhao· 2 shared C. Kerr· 1 shared C. V. Robinson· 1 shared E. Pfitzner· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBiochemistry

F. Duong

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4 papers

Recent·Most cited

Characterisation of membrane protein interactions by peptidisc-mediated mass photometry

J. W. Young, E. Pfitzner, P. Kukura, C. V. Robinson

This study demonstrates the use of peptidiscs with mass photometry to quantify interactions of membrane proteins in detergent-free conditions, showing its effectiveness for studying bacterial membrane complexes and antibody interactions.

iScience · Feb 1, 2024Peer-reviewedBiochemistry

Development of a Method Combining Peptidiscs and Proteomics to Identify, Stabilize and Purify a Detergent-Sensitive Membrane Protein Assembly

J. W. Young, I. S. Wason, Z. Zhao, S. Kim, H. Aoki, S. Phanse, D. G. Rattray, L. J. Foster, M. Babu, F. Duong

The paper develops a method using peptidiscs and proteomics to stabilize and identify detergent-sensitive membrane protein complexes, demonstrating its effectiveness with the E. coli Sec system.

bioRxiv · Mar 3, 2022 · PreprintBiochemistry

Nanodiscs-based proteomics identify Caj1 as an Hsp40 with affinity for phosphatidic acid lipids

X. X. Zhang, J. W. Young, L. J. Foster, F. Duong

The paper uses nanodiscs and proteomics to identify Caj1 as an Hsp40 with specific affinity for phosphatidic acid lipids in yeast.

bioRxiv · Jun 18, 2021Biochemistry

Profiling the E. coli Membrane Interactome Captured in Peptidisc Libraries

J. W. Young, G. Stacey, M. Carlson, I. Wason, Z. Zhao, D. G. Rattray, N. Scott, C. Kerr, M. Babu, L. Foster, F. Duong

This paper uses peptidisc libraries and PCP to profile E. coli membrane interactomes, identifying novel interactions not detectable with detergent-based methods.

bioRxiv · Jul 17, 2019Biochemistry