Hydrogen sulfide release via the ACE inhibitor Zofenopril prevents intimal hyperplasia in human vein segments and in a mouse model of carotid artery stenosis
D. Macabrey, C. Deslarzes-Dubuis, A. Longchamp, M. Lambelet, C. K. Ozaki, J.-M. Corpataux, F. ALLAGNAT, S. Deglise
This paper shows that Zofenopril, an ACE inhibitor that releases hydrogen sulfide, reduces intimal hyperplasia more effectively than other ACE inhibitors in both mice and human vein segments.
bioRxiv · Sep 13, 2021Physiology