G. Pantaleo

ACE2 mimetic antibody potently neutralizes all SARS-CoV-2 variants and fully protects in XBB.1.5 challenged monkeys

Impaired HIV-specific T-cell responses in HIV and S. mansoni coinfected Ugandans.

The paper examines how S. mansoni infection impacts HIV-specific T-cell responses in coinfected Ugandan fishermen, finding reduced immune responses after parasite clearance.

P2G3 human monoclonal antibody neutralizes SARS-CoV-2 Omicron subvariants including BA.4 and BA.5 and Bebtelovimab escape mutants

SARS-CoV-2 Omicron potently neutralized by a novel antibody with unique Spike binding properties

This paper identifies a potent human monoclonal antibody, P2G3, that neutralizes multiple SARS-CoV-2 variants including Omicron, and demonstrates its protective efficacy in a monkey model.

Increased CHIP Prevalence Amongst People Living with HIV

The paper investigates the prevalence of clonal hematopoiesis of indeterminate potential (CHIP) in people living with HIV and finds a higher prevalence compared to controls.

Human follicular CD4 T cell function is defined by specific molecular, positional and TCR dynamic signatures.

CD32+ and PD-1+ Lymph Node CD4 T Cells Support Persistent HIV-1 Transcription in Treated Aviremic Individuals

This study identifies CD32+ CD4 T cells in lymph nodes as a population with persistent HIV-1 transcription, with CD32+PD-1+ cells showing the highest levels in both viremic and treated individuals.