Author

J.-P. H. Borg

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Cancer Biology· 1

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Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

B. H. Habermann· 1 shared F. Ahmad· 1 shared F. Lamballe· 1 shared F. Maina· 1 shared G. B. Mills· 1 shared O. Castellanet· 1 shared S. Lev· 1 shared Y. Vinik· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperCancer Biology

B. H. Habermann

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1 paper

Recent·Most cited

BCL-XL blockage in TNBC models confers vulnerability to inhibition of specific cell cycle regulators

O. Castellanet, F. Ahmad, Y. Vinik, G. B. Mills, B. H. Habermann, J.-P. H. Borg, S. Lev, F. Lamballe, F. Maina

This study shows that blocking BCL-XL makes TNBC cells vulnerable to CDK1/2/4 inhibitors, but not other cell cycle regulators, through synergistic effects on survival and apoptosis pathways.

bioRxiv · Mar 16, 2021Cancer Biology