Author

Y. Vinik

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

F. Ahmad· 2 shared F. Lamballe· 2 shared F. Maina· 2 shared G. B. Mills· 2 shared O. Castellanet· 2 shared S. Lev· 2 shared A. Mueller· 1 shared A.-L. Bailly· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCancer Biology

F. Ahmad

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2 papers

Recent·Most cited

BCL-XL blockage in TNBC models confers vulnerability to inhibition of specific cell cycle regulators

O. Castellanet, F. Ahmad, Y. Vinik, G. B. Mills, B. H. Habermann, J.-P. H. Borg, S. Lev, F. Lamballe, F. Maina

This study shows that blocking BCL-XL makes TNBC cells vulnerable to CDK1/2/4 inhibitors, but not other cell cycle regulators, through synergistic effects on survival and apoptosis pathways.

bioRxiv · Mar 16, 2021Cancer Biology

Modeling Heterogeneity of Triple-Negative Breast Cancer Uncovers a Novel Combinatorial Treatment Overcoming Primary Drug Resistance

F. Lamballe, F. Ahmad, Y. Vinik, O. Castellanet, F. Daian, A. Mueller, U. Koehler, A.-L. Bailly, E. Josselin, R. Castellano, C. Cayrou, E. Charafe-Jauffret, G. B. Mills, V. Geli, J.-P. Borg, , F. Maina

This study develops a mouse model of TNBC that recapitulates human tumor heterogeneity and identifies a synergistic combination of WEE1 and BCL-XL inhibition as a potential treatment.

bioRxiv · Jun 22, 2020Cancer Biology