MDR1 promotes CD8 T cell persistence in tumors and protects against cytotoxic chemotherapy
Lincoln A. Brown, Megan M. Erwin, Natalie R. Favret, Claudia N. McDavid, Jessica J. Roetman, Zachary D. Ewell, Melissa M. Wolf, Kristen A. Murray, Jack E. Smithwick, Marti Goemann, Mary Philip
This study shows that MDR1 promotes CD8 T cell persistence in tumors and protects against chemotherapy-induced cell death.
bioRxiv · Sep 28, 2025 · PreprintImmunology