Author

Jack Xiaoyu Chen

Shanghai Jiao Tong University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Assay:electronic health records· 1 Approach:experimental assay· 1

Frequent Co-Authors

Antonis PapachristodoulouiD· 1 shared Bo Dong· 1 shared Bo ZhangiD· 1 shared Chubin OuiD· 1 shared Cordelia P. N. Rampley· 1 shared Dingyan WangiD· 1 shared Duo AniD· 1 shared Feng Tang· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMicrobiology

Antonis PapachristodoulouORCID

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Author profile →

2 papers

Recent·Most cited

OriGene: A Self-Evolving Virtual Disease Biologist Automating Therapeutic Target Discovery

Zhongyue Zhang, Zijie Qiu, Yingcheng Wu, Sitan Li, Dingyan Wang, Yong Liu, Zhuomin Zhou, Yusong Hu, Yuhan Chen, Duo An, Yongbo Wang, Haijun Yu, Zhenyi Zhong, Chubin Ou, Zichen Wang, , Shuangjia Zheng

OriGene identifies therapeutic targets by integrating diverse data modalities and outperforms human experts and models in accuracy and robustness.

bioRxiv · Jun 3, 2025 · PreprintBioinformatics

Characterisation and development of aspirin inducible biosensors in E. coli Nissle 1917 and SimCells

Jack Xiaoyu Chen, Harrison Steel, Yin-Hu Wu, Yun Wang, Jiabao Xu, Cordelia P. N. Rampley, Ian P. Thompson, Antonis Papachristodoulou, Wei E. Huang

The paper develops an aspirin-inducible gene circuit in E. coli and SimCells, showing dose-dependent induction and competitive binding of SalR variants.

bioRxiv · Sep 11, 2018 · PreprintMicrobiology