Author

Jacob Brenner

Massachusetts General Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Francis Robert· 1 shared Krzysztof J. SzkopiD· 1 shared Nicholas E. Redmond· 1 shared Ola Segnestam LarssoniD· 1 shared Pauline Martin· 1 shared Roberta L. Beauchamp· 1 shared Serkan ErdiniD· 1 shared Sidong HuangiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Francis Robert

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1 paper

Recent·Most cited

TSC2 loss in neural progenitor cells suppresses translation of ASD/NDD-associated transcripts in an mTORC1- and MNK1/2-reversible fashion

Pauline Martin, Krzysztof J. Szkop, Francis Robert, Srirupa Bhattacharyya, Roberta L. Beauchamp, Jacob Brenner, Nicholas E. Redmond, Sidong Huang, Serkan Erdin, Ola Segnestam Larsson, Vijaya Ramesh

This study shows that TSC2 loss in neural progenitor cells suppresses translation of ASD/NDD-associated transcripts, which can be reversed by inhibiting mTORC1 or MNK1/2.

bioRxiv · Jun 4, 2024 · PreprintMolecular Biology