Francis Robert

Loss of MYSM1 deubiquitinase catalytic activity protects against MYC-driven B cell lymphoma via tumor intrinsic effects and indirect modulation of antitumor immunity

This study shows that inhibiting MYSM1's deubiquitinase activity protects against MYC-driven B cell lymphoma through both tumor intrinsic effects and modulation of antitumor immunity.

TSC2 loss in neural progenitor cells suppresses translation of ASD/NDD-associated transcripts in an mTORC1- and MNK1/2-reversible fashion

This study shows that TSC2 loss in neural progenitor cells suppresses translation of ASD/NDD-associated transcripts, which can be reversed by inhibiting mTORC1 or MNK1/2.