Jacob P. Padilla

High Glucose Diet Induces Hepatic Iron Overload Contributing to Metabolic Dysfunction

This study shows that a high glucose diet causes hepatic iron overload in mice, disrupting iron regulation and contributing to metabolic dysfunction, with potential therapeutic implications for iron chelation and metformin use.

Spatial Multiomics Lipids and Gene expression using MALDI In Situ Hybridization Mass Spectrometry Imaging

The paper introduces a new spatial multiomics method combining mRNA detection with lipid analysis using MALDI ISH MSI to link gene expression with metabolic profiles in mouse brain tissue.