Marie C. Heffern

This study investigates the structural and metal binding properties of vimentin tail domain fragments, revealing direct Cu(II) binding to specific regions and providing insights into their role in vimentin function.

This study shows that a high glucose diet causes hepatic iron overload in mice, disrupting iron regulation and contributing to metabolic dysfunction, with potential therapeutic implications for iron chelation and metformin use.

The paper introduces a new spatial multiomics method combining mRNA detection with lipid analysis using MALDI ISH MSI to link gene expression with metabolic profiles in mouse brain tissue.

This study investigates the role of the intestine in metabolic dysregulation in murine Wilson disease by analyzing gut microbiota and lipidome in mouse models.