Author

Nathaniel H. O. Harder

University of California, DavisORCID 0000-0002-5498-3570Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Assay:metagenomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Amanda CaceresiD· 2 shared Marie C. HefferniD· 2 shared Ashok Kumar SharmaiD· 1 shared Austin M. Cole· 1 shared Gaurav V. SarodeiD· 1 shared Guillaume JospiniD· 1 shared Jacob P. Padilla· 1 shared Janine M. LaSalleiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

Amanda CaceresORCID

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2 papers

Recent·Most cited

High Glucose Diet Induces Hepatic Iron Overload Contributing to Metabolic Dysfunction

Amanda Caceres, Nathaniel H. O. Harder, Jacob P. Padilla, Samuel E. Janisse, Austin M. Cole, Sonia E. Roedersheimer, Marie C. Heffern

This study shows that a high glucose diet causes hepatic iron overload in mice, disrupting iron regulation and contributing to metabolic dysfunction, with potential therapeutic implications for iron chelation and metformin use.

iScience · Dec 13, 2025Peer-reviewedBiochemistry

The role of intestine in metabolic dysregulation in murine Wilson disease

Gaurav V. Sarode, Tagreed A. Mazi, Kari E. Neier, Noreene M. Shibata, Guillaume Jospin, Nathaniel H. O. Harder, Amanda Caceres, Marie C. Heffern, Ashok Kumar Sharma, Shyam Kailashrao More, Maneesh Dave, Shannon Schroeder, Li Wang, Janine M. LaSalle, Svetlana Lutsenko, Valentina Medici

This study investigates the role of the intestine in metabolic dysregulation in murine Wilson disease by analyzing gut microbiota and lipidome in mouse models.

Hepatology Communications · Sep 11, 2023Peer-reviewedMolecular Biology