Drosophila Rif1 is critical for repair following P-element excision and influences pathway choice at double-strand breaks
Justin R. Blanch, Manan Krishnamurthy, Jacob T. Zuckerman, Mitch McVey
This study shows Drosophila Rif1 is not essential for general DNA damage repair but is critical for P-element excision-induced double-strand break repair and influences pathway choice by suppressing homologous recombination and promoting single-strand annealing.
bioRxiv · May 24, 2022 · PreprintGenetics