Mitch McVey

This study shows the Drosophila Pol θ linker domain is essential for DNA repair and development, with its function dependent on specific amino acid properties rather than protein interactions.

This study investigates DNA damage tolerance mechanisms in Drosophila melanogaster, showing that translesion synthesis is preferred over template switching for alkylation damage, with REV1 playing a critical role in coordinating this response.

This study shows Drosophila Rif1 is not essential for general DNA damage repair but is critical for P-element excision-induced double-strand break repair and influences pathway choice by suppressing homologous recombination and promoting single-strand annealing.

This study shows that Drosophila PIF1 helicase is essential for survival under replication stress and DNA synthesis during double-strand gap repair, working with POL32 in some contexts but independently in others.