MEF2D impairs mitochondrial respiration, glucose-stimulated insulin secretion, and survival in INS-1 β-cells.
Jacqueline E. Crabtree, Rohit B. Sharma, Jeffery S. Tessem
This study shows that MEF2D overexpression impairs mitochondrial respiration, insulin secretion, and survival in INS-1 β-cells, while knockdown improves these functions.
bioRxiv · Mar 9, 2026 · PreprintCell Biology