Author

Rohit B. Sharma

Weill Cornell MedicineORCID 0000-0002-1435-7612Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:gene regulatory network inference· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Jeffery S. TessemiD· 2 shared Andrew Rappa· 1 shared Christine DarkoiD· 1 shared Jacqueline E. Crabtree· 1 shared Tara Doma Lama· 1 shared Ying Wang· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 11 mutual co-author links

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2 shared papersMolecular Biology

Jeffery S. TessemORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintMar 11, 2026

MEF2A is a negative regulator of β-Cell maturation and function

Ying Wang, Christine Darko, Tara Doma Lama…·Rohit B. Sharma

This study identifies MEF2A as a negative regulator of beta cell maturation and function, showing that its overexpression impairs beta cell identity and insulin secretion under ER stress.

DOI 10.64898/2026.03.09.710500

mousebulk RNA-seq

𝕏 PostBluesky

Cell BiologybioRxivPreprintMar 9, 2026

MEF2D impairs mitochondrial respiration, glucose-stimulated insulin secretion, and survival in INS-1 β-cells.

Jacqueline E. Crabtree, Rohit B. Sharma, Jeffery S. Tessem

This study shows that MEF2D overexpression impairs mitochondrial respiration, insulin secretion, and survival in INS-1 β-cells, while knockdown improves these functions.

DOI 10.64898/2026.03.07.709963

mousebulk RNA-seq

𝕏 PostBluesky