Optical activation of midbrain dopamine neurons: do high and low stimulation frequencies produce functionally different effects?
Jacques Voisard, Marie‐Pierre Cossette, Andreas Arvanitogiannis, Peter Shizgal
The paper investigates whether 20- and 50-Hz optical stimulation of midbrain dopamine neurons produce functionally distinct effects, finding that differences are quantitative rather than qualitative and related to reward intensity.
bioRxiv · Apr 9, 2025 · PreprintNeuroscience