Convergent effects of neurodevelopmental disorder-associated variants at mitochondria
Maxine I. Robinette, Jada B. Gundy, Xinyan Leng, Duc Duong, Anantharaman Shantaraman, Liang Shi, Elizabeth Arnulfo Candelario, Anson David Sing, Shubhangi Vibhor Garg, Weibo Niu, Nicholas T. Seyfried, Steven A. Sloan, Zhexing Wen, Joseph F. Cubells, Erica Nichole Duncan, , Ryan H. Purcell
The paper investigates how neurodevelopmental disorder-associated variants affect mitochondrial proteins and finds convergent effects on mitochondrial translation in two high-risk CNVs.
bioRxiv · Feb 27, 2026 · PreprintNeuroscience