Reporter CRISPR screens decipher cis- and trans-regulatory principles at the Xist locus
Till Schwämmle, Gemma Noviello, Eleni Kanata, Jonathan J. Froehlich, Melissa Bothe, Aybuge Altay, Jade Scouarnec, Vivi-Yun Feng, Martin Vingron, Edda G. Schulz
The paper uses CRISPR screens to identify transcription factors regulating Xist expression and their interactions with cis-regulatory elements during X-chromosome inactivation.
bioRxiv · Oct 8, 2024 · PreprintGenetics