Author

Jonathan J. Froehlich

Max Delbrück CenterORCID 0000-0002-9176-4633Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 2 Approach:experimental assay· 2 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Altuna AkaliniD· 1 shared Aybuge AltayiD· 1 shared Bora UyariD· 1 shared Edda G. SchulziD· 1 shared Eleni KanataiD· 1 shared Gemma NovielloiD· 1 shared Jade Scouarnec· 1 shared Kathrin TheiliD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenetics

Altuna AkalinORCID

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2 papers

Recent·Most cited

Reporter CRISPR screens decipher cis- and trans-regulatory principles at the Xist locus

Till Schwämmle, Gemma Noviello, Eleni Kanata, Jonathan J. Froehlich, Melissa Bothe, Aybuge Altay, Jade Scouarnec, Vivi-Yun Feng, Martin Vingron, Edda G. Schulz

The paper uses CRISPR screens to identify transcription factors regulating Xist expression and their interactions with cis-regulatory elements during X-chromosome inactivation.

bioRxiv · Oct 8, 2024 · PreprintGenetics

Parallel genetics of regulatory sequences in vivo

Jonathan J. Froehlich, Bora Uyar, Margareta Herzog, Kathrin Theil, Petar Glažar, Altuna Akalin, Nikolaus Rajewsky

The paper functionally analyzes regulatory sequences in C. elegans by introducing mutations and measuring their effects on gene expression and fitness.

Cell Reports · Apr 1, 2021Peer-reviewedGenetics