Phosphoserine aminotransferase SerC is a central metabolic checkpoint and druggable vulnerability in Mycobacterium tuberculosis
Michael James Perret, Tom A. Mendum, Daniel J. Kim, Jade Seng, Brian D. Robertson, Rebecca Winsbury, Simon M. Clark, Johnjoe McFadden, Khushboo Borah
This study identifies SerC as a critical metabolic enzyme in Mtb, showing its essential role in survival and revealing it as a potential drug target for TB therapy.
bioRxiv · Mar 28, 2026 · PreprintMicrobiology