Author

Jade-Emmanuelle Deshaies

Centre Hospitalier de l’Université de Montréal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Christine Vande VeldeiD· 2 shared Alicia F. DubinskiiD· 1 shared Alyssa N. CoyneiD· 1 shared Anaïs AulasiD· 1 shared Andréanne Lacombe· 1 shared Anna‐Leigh BrowniD· 1 shared Arash Meghdadi Esfahani· 1 shared Asmita GhoshiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersNeuroscience

Christine Vande VeldeORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintSep 17, 2025

TDP-43 pathology triggers SRRM4-dependent cryptic splicing of G3BP1 in ALS/FTD

Hana Fakim, Asmita Ghosh, Emmanuel Amzallag…·Christine Vande Velde

The paper shows that TDP-43 pathology causes a cryptic exon in G3BP1 to be included in neurons, leading to a protein that disrupts stress granule dynamics in ALS/FTD.

3 citations

humanbulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintSep 15, 2020

TDP-43 stabilizes transcripts encoding stress granule protein G3BP1: potential relevance to ALS/FTD

Hadjara Sidibé, Yousra Khalfallah, Shangxi Xiao…·Christine Vande Velde

This study shows TDP-43 stabilizes G3BP1 transcripts via direct binding, and TDP-43 depletion reduces G3BP1 protein levels, contributing to stress granule dysfunction in ALS/FTD.

3 citations

humanexperimental assay

𝕏 PostBluesky