Development of Recombinant Anti-TLR2 Antibodies and PLGA Nanoparticle-based Gene Therapy for the Treatment of Neuropathic Pain
Subeen Lee, Jaekyung Jeon, Hyunji Lee, Ellane Eda Barcelon, Jinpyo Hong, Sung Joong Lee
This paper develops a PLGA nanoparticle-based gene therapy to deliver anti-TLR2 antibodies for neuropathic pain treatment, showing sustained analgesia in mouse models.
Molecular Therapy · Jul 29, 2026Peer-reviewedNeuroscience