Author

Jinpyo Hong

Korea Institute of Science and TechnologyORCID 0000-0002-4776-4396Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Changjoon Justin LeeiD· 2 shared Jaekwang LeeiD· 2 shared Junsung WooiD· 2 shared Doo‐Wan ChoiD· 1 shared Ellane Eda BarceloniD· 1 shared Heejung ChuniD· 1 shared Heeyoung AniD· 1 shared Hoon RyuiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersNeuroscience

Changjoon Justin LeeORCID

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3 papers

Recent·Most cited

TRANsCre-DIONE transdifferentiates scar-forming reactive astrocytes into functional motor neurons

Heeyoung An, Hye-Lan Lee, Doo‐Wan Cho, Jinpyo Hong, Hye Yeong Lee, Jung Moo Lee, SunYeong Choi, In‐Young Hwang, Junsung Woo, Jaekwang Lee, Mingu Park, Young‐Su Yang, Su-Cheol Han, Yoon Ha, Changjoon Justin Lee

This paper describes a method to convert reactive astrocytes into functional motor neurons with high efficiency and specificity using TRANsCre-DIONE, leading to improved motor recovery in spinal cord injury.

Experimental & Molecular Medicine · Sep 11, 2026Peer-reviewedNeuroscience

Development of Recombinant Anti-TLR2 Antibodies and PLGA Nanoparticle-based Gene Therapy for the Treatment of Neuropathic Pain

Subeen Lee, Jaekyung Jeon, Hyunji Lee, Ellane Eda Barcelon, Jinpyo Hong, Sung Joong Lee

This paper develops a PLGA nanoparticle-based gene therapy to deliver anti-TLR2 antibodies for neuropathic pain treatment, showing sustained analgesia in mouse models.

Molecular Therapy · Jul 29, 2026Peer-reviewedNeuroscience

Astrocytes render memory flexible

Wuhyun Koh, Mijeong Park, Ye Eun Chun, Jaekwang Lee, Hyun Soo Shim, Mingu Gordon Park, Sunpil Kim, Moonsun Sa, Jinhyeong Joo, Hyunji Kang, Soo‐Jin Oh, Junsung Woo, Heejung Chun, Seung Eun Lee, Jinpyo Hong, , Changjoon Justin Lee

This study shows astrocytes regulate NMDAR tone through Best1-mediated glutamate and D-serine release, which is essential for cognitive flexibility and memory repotentiation during reversal learning.

Biological Psychiatry · Oct 21, 2021Peer-reviewedNeuroscience