Author

Sung Joong Lee

Seoul National UniversityORCID 0000-0002-4102-002XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Hye Won Jun· 2 shared Junseo Park· 2 shared Ellane Eda BarceloniD· 1 shared Hyunji Lee· 1 shared Jaekyung Jeon· 1 shared Jinpyo HongiD· 1 shared Jun Seo ParkiD· 1 shared Kwang Hwan KimiD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersNeuroscience

Hye Won Jun

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Author profile →

4 papers

Recent·Most cited

Peripheral nerve injury induces an immunometabolic signature involving reduced free fatty-acid pools

Junseo Park, Hye Won Jun, Sung Joong Lee

The paper identifies an immunometabolic signature in the spinal cord after peripheral nerve injury, showing reduced free fatty acid pools and upregulated immune programs.

Metabolic Brain Disease · Aug 17, 2026Peer-reviewedNeuroscience

Development of Recombinant Anti-TLR2 Antibodies and PLGA Nanoparticle-based Gene Therapy for the Treatment of Neuropathic Pain

Subeen Lee, Jaekyung Jeon, Hyunji Lee, Ellane Eda Barcelon, Jinpyo Hong, Sung Joong Lee

This paper develops a PLGA nanoparticle-based gene therapy to deliver anti-TLR2 antibodies for neuropathic pain treatment, showing sustained analgesia in mouse models.

Molecular Therapy · Jul 29, 2026Peer-reviewedNeuroscience

Astrocytic glycogenolysis gates Warburg-like metabolic reprogramming that promotes neuropathic pain chronification

Junseo Park, Kwang Hwan Kim, Hye Won Jun, Se‐Young Choi, Seung Bum Park, Sung Joong Lee

This paper identifies astrocytic glycogenolysis as a metabolic switch that promotes neuropathic pain chronification and shows that inhibiting it reduces pain without impairing acute nociception.

Progress in Neurobiology · May 2, 2026Peer-reviewedNeuroscience

Reverse target screening identifies putative L-AAA targets in astrocyte-selective toxicity

Jun Seo Park, Sung Joong Lee

The paper identifies pyruvate carboxylase as a potential target of L-AAA, explaining its astrocyte-selective toxicity through metabolic disruption.

bioRxiv · Oct 21, 2025 · PreprintBiochemistry