Author

Jaisen Lim

University of California San Diego

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 1

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Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Don W. ClevelandiD· 1 shared Haiyang Yu· 1 shared John R. YatesiD· 1 shared John RavitsiD· 1 shared Jolene K. DiedrichiD· 1 shared Lilian Gao· 1 shared Michael W. BaughniD· 1 shared Shan LuiD· 1 shared

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2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Don W. ClevelandORCID

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1 paper

Recent·Most cited

Acetylation of lysine 82 initiates TDP-43 nuclear loss of function by disrupting its nuclear import

Sitao Zhang, Sonia Vazquez‐Sanchez, Shan Lu, Michael W. Baughn, Jaisen Lim, Spencer Oung, Lilian Gao, Jolene K. Diedrich, John R. Yates, Haiyang Yu, John Ravits, Don W. Cleveland

This study identifies acetylation of lysine 82 in TDP-43 as a mechanism causing nuclear loss of function and cytoplasmic accumulation, linked to neurodegenerative diseases like ALS.

bioRxiv · Sep 4, 2024 · PreprintNeuroscience