Alternative splicing broadens antiviral diversity at the human OAS2 locus
Emma L. Davies, Alegna Calderon Nuñez, Allison L Ward, Hanna Sowar, Eilidh Rivers, Arda Balci, Daniel Mair, Elliot Moorhouse, Jake Towers, Arthur Wickenhagen, Matthew L. Turnbull, Massimo Palmarini, Sam J. Wilson, Adam J. Fletcher
The paper shows that alternative splicing of the OAS2 gene generates two antiviral proteins with distinct target specificities and mechanisms.
The EMBO Journal · Jun 3, 2026Peer-reviewedMicrobiology