PGC-1β prevents statin-associated myotoxicity in oxidative skeletal muscle
François Singh, Joffrey Zoll, Urs Duthaler, Anne-Laure Charles, Gilles Laverny, Daniel Metzger, Bernard Geny, Stephan Krähenbühl, Jamal Bouitbir
This study shows that PGC-1β protects oxidative skeletal muscle from statin-induced damage by maintaining mitochondrial function and preventing apoptosis.
bioRxiv · Nov 13, 2017 · PreprintPharmacology & Toxicology