Daniel METZGER

This study shows that satellite cell glucocorticoid receptor (GR) maintains quiescence but does not mediate therapeutic GC effects on muscle repair, highlighting the importance of treatment timing and context.

This study shows that androgen receptor signaling regulates beige adipocyte remodeling, mitochondrial function, and metabolic adaptation in male mice.

This study shows that glucocorticoid receptor signaling in myeloid cells affects inflammation resolution and muscle repair by regulating macrophage dynamics and satellite cell function.

This study shows androgen receptor signaling maintains skeletal muscle stem cell quiescence and regenerative capacity, and its loss leads to premature activation and stem cell depletion.

This study shows that glucocorticoid receptor (GR) interacts with androgen receptor (AR) to regulate prostate epithelial homeostasis through shared cis-regulatory elements.

This study identifies castration-tolerant Club-like cells in prostate cancer and shows that targeting FOSL1/AP-1 and PIM kinases reduces their progenitor properties and tumor growth.

This study optimises C-protein-induced myositis by immunising mice with a specific C-protein polypeptide, resulting in a reproducible and stable model of inflammatory myopathy with key pathological features.

This study investigates Thio-2's mechanism of action in inhibiting AR signaling in CRPC, showing it acts independently of BAG-1 isoforms and with potential AR NTD binding.

This study shows that reducing RyR1 in mice causes muscle weakness, atrophy, and structural changes similar to Central Core Disease.

This study shows that PGC-1β protects oxidative skeletal muscle from statin-induced damage by maintaining mitochondrial function and preventing apoptosis.