HIV and FIV glycoproteins increase cellular tau pathology via cGMP-dependent kinase II activation
Matheus Figueiredo Sathler, Michael J. Doolittle, James A. Cockrell, India R. Nadalin, Franz Bruno Hofmann, Sue VandeWoude, Seonil Kim
This study shows HIV and FIV glycoproteins increase tau pathology in neurons through cGMP-dependent kinase II activation, suggesting a link between HIV infection and accelerated Alzheimer's-like pathology.
Journal of Cell Science · May 31, 2022Peer-reviewedNeuroscience