Matheus Figueiredo Sathler

This study shows that prenatal valproic acid exposure reduces δ-catenin levels and disrupts synaptic function and ultrasonic vocalization in mice, linking these changes to autism spectrum disorder.

This paper investigates how the G34S mutation in δ-catenin causes loss of function leading to social dysfunction in ASD by altering glutamatergic activity and GSK3β-mediated degradation.

This study shows HIV and FIV glycoproteins increase tau pathology in neurons through cGMP-dependent kinase II activation, suggesting a link between HIV infection and accelerated Alzheimer's-like pathology.

This study shows that phosphorylation of GluA1 at S845 reduces AP2 binding, decreasing AMPAR endocytosis and increasing surface expression during synaptic plasticity.

This study shows that cGKII knockout mice exhibit altered ultrasonic vocalizations and hypothalamic neuron activation, suggesting they model speech impairment in human 4q21 microdeletion syndrome.