Histone H2A Ubiquitination Mediates the Establishment of Reactivation-Competent HSV-1 Latent Infection
James Boehlke, Sara Anna Dochnal, Chandra Shekhar Misra, Alison K. Francois, Chris Boutell, Anna Ruth Cliffe
This study shows that H2AK119ub1, deposited by PRC1, is critical for HSV-1 reactivation from latency, while H3K27me3 is not.
bioRxiv · Nov 23, 2025 · PreprintMicrobiology