Author

James Empfield

Xenon Pharmaceuticals (Canada)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Aaron D. Williams· 1 shared Charles J. Cohen· 1 shared Fiona ScottiD· 1 shared James P. JohnsoniD· 1 shared Janette Mezeyova· 1 shared Maegan Soriano· 1 shared Matthew Waldbrook· 1 shared Mohammad‐Reza GhovanlooiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

Aaron D. Williams

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1 paper

Recent·Most cited

Pharmacology & ToxicologyACS Chemical NeurosciencePeer-reviewedFeb 15, 2024

Molecular pharmacology of selective NaV1.6 and dual NaV1.6 and NaV1.2 channel inhibitors that suppress excitatory neuronal activity ex vivo

Samuel J. Goodchild, Noah Gregory Shuart, Aaron D. Williams…·James P. Johnson

This paper introduces selective NaV1.6 and dual NaV1.6/NaV1.2 inhibitors that suppress excitatory neuronal activity ex vivo, showing selectivity over NaV1.1 and efficacy in seizure models.

36 citationstop 4%

electrophysiologyexperimental assay

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